[Products Name] Exenatide Acetate
[Molecular Formula] C187H282N50O60S
[CAS No.] 141732-76-5
[Product Description]
Appearance :White powder
Water Content(Karl Fischer) :≤5.0%
Acetate Content(by HPLC) :≤12.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N ) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
Pharmacologic class: Incretin mimetic
Therapeutic class: Hypoglycemic
Pregnancy risk category C
[Action]
Mimics enhancement of glucose-dependent insulin secretion and several other antihyperglycemic actions of incretins.
[Precautions]
Use cautiously in:
1. severe renal impairment or end-stage renal disease, acute pancreatitis, severe GI disease
2. concurrent use of insulin, thiazolidinediones, D-phenylalanine derivatives, meglitinides, or alpha-glucosidase inhibitors
3. pregnant or breastfeeding patients
4. children (safety and efficacy not established).
