Product name:Epothilone B
Synonym: EPO906, EpoB, Patupilone
Molecular Formula: C27H41NO6S
Molecular Weight:507.68
CAS Number: 152044-54-7
Appearance:Colorless crystals
Purity (HPLC):≥99.0%
Descriptions: A compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Epothilone B may cause complete cell-cycle arrest.
