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DNA ligase

DNA ligase

  Product name: DNA ligase
  EC number: EC 6.5.1.1
  Product Description:
  In molecular biology, DNA ligase is a special type of ligase (EC 6.5.1.1) that can link together two DNA strands that have double-strand break (a break in both complementary strands of DNA). The alternative, a single-strand break, is fixed by a different type of DNA ligase using the complementary strand as a template but still requires DNA ligase to create the final phosphodiester bond to fully repair the DNA.
  DNA ligase has applications in both DNA repair and DNA replication (see Mammalian ligases). In addition, DNA ligase has extensive use in molecular biology laboratories for Genetic recombination experiments.


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